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Spheronizer or Twin Spheronizer

Spheronizer

  • Spheronization is a key step in Granulation/Palletization after extrusion that uses a compact high-speed machine to produce spherical pellets.
  • In this process extruded vermicelli is dropped into a bowl with a rotating chequered plate.
  • The tangential and centrifugal forces cause the vermicelli to break into pieces which then collide with the machine’s cylindrical walls.
  • The rolling action at the outer edge of the spheronizer forms these fragments into spheres.
  • The final pellet size and surface quality depend on factors such as batch size / machine speed / processing time / the properties of the extrudate and the pitch of the chequered plates.

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Detailed Information on Spheronizer or Twin Spheronizer

A Spheronizer is a specialized pharmaceutical machine used primarily for the production of spherical pellets or beads from extruded or granulated materials. Spheronization is the necessary step of Granulation by extrusion. It's a self-contained compact machine designed to deliver Spherical Pellets at fast production rates. It is a process where the preformed Vermicelli once dropped in the bowl & exposed to a rotating Chequered Plate, are fragmented into pieces - equal length of diameter of Extruders, because of the tangential & centrifugal force, they collide with the cylindrical walls of the spheronizer. Finally the rope-type movement of the extrudes at the outer border give a rolling action on the fragmented extrudes & converts them into spheres. FEATURES Function: The spheronizer converts extrudes into spheroids, a crucial step in the extrusion-spheronization process, turning pharmaceutical products into small, uniform spheres. Structure: It features a rotating chequered plate with cross-hatched grooves inside a cylindrical bowl. Design: The radial clearance between the plate and the bowl is minimal (<0.3 mm) to prevent powder leakage. Purging air is used to avoid powder falling through and to help evaporate excess moisture. Process: As the plate rotates, the extrudes are fragmented into pieces. These fragments are rolled into spheres by colliding with the bowl's wall and the rotating action. Discharge: Once the particles are spheroidized, they are centrifugally discharged through a door into a hopper. Versatile Capacities: Handles batch sizes from 100 gram to 50 kg for industrial production. cGMP Compliance: Available in cGMP-compliant and standard models. Custom Materials: Contact parts in SS 316, SS 304, or MS, as per customer choice. Varied Chequered Plates: Offers pitch options ranging from 1 mm to 6.5 mm for customized pellet size and quality. Advanced Drive System: AC frequency variable drives for precise control. Precision Design: Minimal clearance between bowl and plate for optimal performance. PERKS 1. Reduces Dusting: Minimizes dust and fines during processing. 2. Smooth Surface: Produces granules with a smooth, uniform surface. 3. Enhanced Stability: Densifies granules for better stability. 4. Efficient Coating: Requires less coating material. 5. Improves Flow: Enhances flowability of granules. 6. Increases Bulk Density: Boosts the bulk density of the final product.

ModelUSPH-150USPH-250USPH-380USPH-500USPH-700USPH-900USPH-1100
Capacity 50-100 gm/hr 250-500 gm/hr 1-2 kg/hr 2-5 kg/hr 7-8 kg/hr 11-15 kg/hr 25-50 kg/hr

Highlights of Spheronizer or Twin Spheronizer

  • - Compact design acquires limited footprint and GMP Suites pellet production.
  • - System components easily accessible for cleaning and maintenance.
  • - Interchangeable Chequered Plate attachments allows to produce Diffferent Sizes of Spheres/Pellets.
  • - Complete process Automation with PLC controls & HMI.
  • - Minimal Radial Clearance between Plate & Bowl.
  • - Pneumatically controlled Auto Discharge.

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FAQs on Spheronizer or Twin Spheronizer

A Spheronizer is used to convert cylindrical extrudates into smooth, spherical pellets. It is a critical step in the extrusion-spheronization process and is widely used in pharmaceutical, nutraceutical, agrochemical, and specialty chemical industries for pellet production.

During spheronization, extrudates are introduced into a rotating bowl containing a chequered friction plate. The combined action of centrifugal and tangential forces breaks the extrudates into uniform segments and rolls them into spherical pellets with excellent shape and surface characteristics.

Pellet size distribution and surface finish are influenced by several parameters, including extrusion quality, batch size, plate speed, processing time, product characteristics, and the pitch design of the chequered plate.

A Spheronizer produces highly spherical pellets with excellent flow properties, uniform size distribution, improved coating efficiency, enhanced drug release control, and higher process yields while maintaining product consistency.

Yes, cysteine beadlets can be customized with different particle sizes ranging from <0.2mm to 5.0mm, release profiles, and color

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